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Publishing success for CHIRI’s cancer researchers

By Amanda Iannuzzi 10 January 2019 News Comments off
The two journal covers.

The two journal covers, the first featuring a cover image from the article by CHIRI researchers.

Former PhD student Dr Sebastian Pohl and his Curtin Health Innovation Research Institute (CHIRI) colleagues have recently had two articles published in premiere redox biology journals. Redox biology has been demonstrated to be critical in the understanding of cancer progression, as well as being studied in the development of therapeutics. Changes in the levels of different antioxidants within cancers cells can be both beneficial or detrimental for cancer growth.

Sebastian was lead author of both articles, with contributions from two of his CHIRI co-supervisors Professor Arun Dharmarajan and Senior Research Fellow Dr Mark Agostino, in collaboration with Prof. Shazib Pervaiz (National University of Singapore). Read more…

CHIRI involvement soars as ASI meeting returns to Perth

By Amanda Iannuzzi 14 December 2018 News Comments off
Dr Connie Jackaman, Jeanne Edmands, Dr Mark Agostino, Lelinh Duong, A/Prof. Delia Nelson and Prof. Deirdre Coombe.

Dr Connie Jackaman, Jeanne Edmands, Dr Mark Agostino, Lelinh Duong, A/Prof. Delia Nelson and Prof. Deirdre Coombe.

The Australasian Society for Immunology’s (ASI) Annual Scientific Meeting returned to Perth for the first time in eight years this December.

The annual meeting of this broad-based society focused on supporting the discipline of immunology, is rotated around Australia and New Zealand. The meeting was last held in Western Australia in 2010.

For the past three years, staff and students from the Curtin Health Innovation Research Institute (CHIRI) and Curtin’s School of Pharmacy and Biomedical Sciences have been heavily involved in organising the national meeting – Dr Connie Jackaman as the meeting’s Chair, as well as Jeanne Edmands, Dr Mark Agostino, A/Prof Delia Nelson and student representative Lelinh Duong.

This year, approximately 420 delegates attended the meeting across five days. Highlights of the meeting included a dynamic scientific program filled with outstanding international and national speakers, as well as the vibrant conference dinner sponsored by CHIRI. Read more…

CHIRI researchers celebrate $2.24 million NHMRC funding boost

By Amanda Iannuzzi 13 December 2018 News Comments off
Prof. Melinda Fitzgerald and A/Prof. Nina Tirnitz-Parker.

Prof. Melinda Fitzgerald and A/Prof. Nina Tirnitz-Parker.

Two Curtin Health Innovation Research Institute (CHIRI) researchers received a total of more than $2.24 million in funding from the latest round of National Health and Medical Research Council (NHMRC) grants.

Professor Melinda (Lindy) Fitzgerald (CHIRI/Perron Institute for Neurological and Translational Sciences) received $1,245,138 as the chief investigator of a research project looking to define the unifying mechanisms of oxidative damage to oligodendrocyte DNA in neurotrauma, neurodegenerative and demyelinating disease.

As the chief investigator of a research project targeting the TWEAK/Fn14 signalling pathway as a novel therapeutic strategy to prevent chronic liver disease progression, Associate Professor Nina Tirnitz-Parker (School of Pharmacy and Biomedical Sciences), received $997,485. Read more…

Be our guest: CHIRI researcher edits two cancer journal special issues

By Amanda Iannuzzi 13 December 2018 News Comments off
Professor Arun (Dharma) Dharmarajan.

Professor Arun (Dharma) Dharmarajan.

Curtin Health Innovation Research Institute (CHIRI) cancer researcher Professor Arun (Dharma) Dharmarajan (from Curtin’s School of Pharmacy and Biomedical Sciences) is guest editing special issues of two international research journals.

The first is a special issue on ‘Cancer Stem Cells’ for the International Journal of Biochemistry and Cell Biology (Impact factor 3.2) and the second on ‘Apoptosis in Cancer’ for the journal Cancers (Impact Factor 5.3).

Dharma says the past decade has produced remarkable advances in understanding cancer biology in particular cancer stem cells and cancer genetics. Read more…

Mark’s a medallist!

By Amanda Iannuzzi 12 December 2018 News Comments off
Dr Mark Hackett.

Dr Mark Hackett.

Congratulations to the Curtin Health Innovation Research Institute’s (CHIRI) Dr Mark Hackett from Curtin’s School of Molecular and Life Sciences on receiving the Royal Australian Chemical Institute (RACI) Analytical and Environmental Chemistry Division Paul Haddad Medal.

The medal recognises Mark’s research and contribution to analytical and environmental chemistry, both nationally and internationally, in particular his development of new imaging techniques for neuroscientists.

Read more…

Plenty of CHIRI research to digest at national workshop

By Amanda Iannuzzi 12 December 2018 News Comments off
Julia Koehn,  Nur Dianah Binte Abu Bakar, Silvano Paternosta, Gayatri Shirolkar, Dr Ross Graham, Dr Caryn Elsegood, Francis Gratte, Prof. Marco Falasca, Dr Rodrigo Carlessi, Dr Alice Domenichini, Ilaria Casari and A/Prof. Nina Tirnitz-Parker.

Julia Koehn, Nur Dianah Binte Abu Bakar, Silvano Paternoster, Gayatri Shirolkar, Dr Ross Graham, Dr Caryn Elsegood, Francis Gratte, Prof. Marco Falasca, Dr Rodrigo Carlessi, Dr Alice Domenichini, Ilaria Casari and A/Prof. Nina Tirnitz-Parker.

The involvement of several Curtin Health Innovation Research Institute (CHIRI) researchers in the recent Gastroenterological Society of Australia’s (GESA) 2018 Research Workshop in Surfers Paradise helped to ensure a swell event.

The workshop, convened by CHIRI Associate Professor Nina Tirnitz-Parker, from Curtin’s School of Pharmacy and Biomedical Sciences, and Professor Nicholas Shackel from the Ingham Institute in Sydney, provides a forum for the Australian Gastroenterology and Hepatology communities to exchange ideas and forge collaborations between GESA investigators, MD and PhD scholars, and postgraduate, basic and clinician scientists.

CHIRI’s Professor Marco Falasca was invited to speak on progress in pancreatic cancer research, while Dr Rodrigo Carlessi, Dr Ross Graham and Dr Alice Domenichini (all from the School of Pharmacy and Biomedical Sciences) chaired sessions. Read more…

Wish to progress dementia research granted

By Amanda Iannuzzi 11 December 2018 News Comments off
Ayeisha Milligan Armstrong.

Ayeisha Milligan Armstrong.

Curtin Health Innovation Research Institute (CHIRI) Work Experience Volunteer Ayeisha Milligan Armstrong has been awarded a highly-prized 2018 Dementia Centre for Research Collaboration (DCRC) Postgraduate Scholarship.

Ayeisha, who is a former CHIRI Honours student, received one of only three of the highly-competitive scholarships awarded nationally this year. She will use the scholarship of $30,000 a year for three years to investigate links between chronic stress and increased risk of cognitive decline seen in cases of Alzheimer’s disease (AD).

Ayeisha’s research will be co-supervised by CHIRI’s Associate Professor David Groth and A/Professor Giuseppe Verdile, as well as A/Professor Simon Laws from ECU and the Ralph and Patricia Sarich Neuroscience Research Institute. Read more…

Clinical trial of cannabis compound for pancreatic cancer treatment

By Amanda Iannuzzi 4 December 2018 News Comments off
Prof. Marco Falasca.

Prof. Marco Falasca.

“We could make that little bit of hope a bit bigger,” says Curtin Health Innovation Research Institute (CHIRI) researcher Professor Marco Falasca, on news his potential new treatment for pancreatic cancer is moving into clinical trials.

Curtin University is conducting the clinical trials, which will see pancreatic cancer patients in Western Australia offered a medicinal cannabis compound.

This step follows encouraging results in laboratory tests, which have Marco hopeful he has found a way of halting the progression of what is one of the most deadly forms of cancer.

Read more about Marco’s research and the trials in the article Cannabis compound gives hope to patients with pancreatic cancer.

SWAN gone for another year but not forgotten

By Amanda Iannuzzi 4 December 2018 News Comments off
CHIRI Director Prof. John Mamo, Prof. Manny Noakes and Prof. Lindy Fitzgerald.

CHIRI Director Prof. John Mamo, Prof. Manny Noakes and Prof. Lindy Fitzgerald.

 

Another successful Symposium of Western Australian Neuroscience (SWAN) may be behind us but it’s fresh in the minds of many at the Curtin Health Innovation Research Institute (CHIRI) who are celebrating their involvement in the two-day event.

A total of around 190 people participated at various stages throughout the program, which featured an impressive line-up of international, national and local speakers, covering areas of neuroscience including dementia, neurotrauma, demyelinating disorders, sensory neuroscience, neuroscience of addiction, neuromuscular conditions, stroke and movement.

CHIRI sponsored the event, including a public lecture by internationally-recognised key opinion leader and trusted advisor in nutrition and health, Professor Manny Noakes, was well-attended and, as the topic promised, provided much food for thought. Read more…

Get in sync with Clinton’s research at WA symposium

By Amanda Iannuzzi 30 November 2018 News Comments off
Clinton Kidman.

Clinton Kidman.

If you’re heading to the 5th WA Synchrotron Symposium at Curtin University today, be sure to catch Curtin Health Innovation Research Institute (CHIRI) PhD student Clinton Kidman talk about how he’s using synchrotron science to explore the link between iron and fatty liver disease.

Clinton is among a team of CHIRI researchers using the Australian Synchrotron facility in Melbourne to measure the concentration and distribution of fat and other organic molecules in the liver at a resolution and sensitivity not possible with other techniques. The team also uses Australia’s Nuclear Science and Technology Organisation’s facility at Lucas Heights to measure iron. Read more…

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